Harnessing epigenetics for healthy aging and increased health span
Aging is a natural and complex biological program characterized by a gradual decline in physiological and mental fitness and increasing susceptibility to disease.
Vital processes including metabolism, inflammation, and epigenetics converge to shape senescence of cells and organs. Epigenetic signals mirror aging processes and epigenetic actuators shape the biology of aging.
This provides unique opportunities to strengthen resilience, balance biological processes, and fend off undesirable exacerbations of aging.
Disruptive potential of epigenetic actuators
Epigenetic factors play a proven active role in aging and senescence.
Epigenetic changes are by nature reversible and integrate known measures and interventions that enable healthy aging and increased health span.
Epigenetic factors drive inflammation and energy metabolism – both hallmarks of aging and senescence.
Nutrition, caloric restriction, and exercise exert their health benefits through epigenetic mechanisms, which counteract decline of fitness and health.
epiQ.bio built FastTrack- and DeepTrack-Screening capabilities that enable industry-scale identification and quantitative validation of small molecule modulators of epigenetic modifiers of healthy aging.
epiQ.bio can screen compound libraries comprising natural and synthetic molecules, that can serve as bioactives with proven bioactivity and market-disruptive potential.
Succesful proof-of-concept validation of small molecules that target epigenetic modifiers involved in aging and senescence.
Activating Cellular Repair ...
Tempering Immune Reactions....
Taming Aging Mechanisms ...
... with natural products and bioactives
Aging-related morbidity is rooted in molecular programs encoded in our genome and brought to action by specific regulatory factors including epigenetic actuators. Activity of these aging-related factors can be modulated by small molecule bioactives including natural products in order to balance their healthspan shortening activities.
epiQ.bio develops bioassays to quantitatively assess and validate bioactivity of small molecule modulators of epigenetic actuators involved in healthy aging. epiQ.bio further enables industry-scale screening of small molecule libraries and identification of aging-related bioactives from natural ressources.
Modulating the activity of EpiGenetic Factors with Natural Compounds
